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2021-6-17 · IGFBP-1 is not usually present in the vagina, but after rupture of fetal membranes, amniotic fluid with a high concentration of IGFBP-1 mixes with vaginal secretions. In StrongStep® PROM test, a specimen of vaginal secretion is taken with a sterile polyester swab and the specimen is extracted into Specimen Extraction Solution.
Get PriceDescription. Designed for professional use and in vitro diagnostic. Rapid chromatographic immunoassay test for the qualitative detection of IGFBP-1 (insulin-like growth factor binding protein 1), a major protein marker in amniotic fluid, in a vaginal swab.. RELIABLE: Sensitivity (true positive rate): 97.6%
Get Price2017-7-21 · the IGFBP-1 bedside test can be used for the diagnosis of PROM in women with or without bleeding both at term and preterm. Kallioniemi et al, 2014 “ ” Unlike other diagnostic tests, gestational age will not affect the accuracy in detecting the presence of IGFBP-1 since the high amniotic fluid-serum ratio of IGFBP-1 is retained from the second
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Get Price2020-1-13 · IGFBP-1-AFP rapid test with standard PROM examination (r=0.841, p=0.000) was higher than the correlation coefficient of IGFBP-1-AFP rapid test with standard PROM examination (r=0.772, p=0.000). Conclusion: Combined IGFBP-1-AFP rapid test has a better diag-nostic value than IGFBP-1 rapid test alone. [Indones J Obstet Gynecol 2015; …
Get Price2018-11-26 · PROM from vaginal fluid 4 (Figure 1). The majority of diagnostic PROM tests detect insulin-like growth factor binding protein-1 (IGFBP-1) present in vaginal ... * The Actim® PROM test has an IGFBP-1 measurement range of 400–8,000,000 µg/L. 400 µg/L corresponds to 25 µg/L in extracted sample.
Get PriceActim PROM test is a visually interpreted, qualitative immunochromatographic dipstick test for detection of amniotic fluid in vaginal secretions during pregnancy. Actim PROM detects IGFBP-1, which is a major protein in amniotic fluid and a marker of the amniotic fluid in a vaginal sample.
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Get Price2013-3-1 · In this study, the sensitivity and the specificity of IGFBP-1 (Actim PROM test®) in diagnosing PROM were 89.3% & 82.7%, respectively, as compared with 84% sensitivity & 78.7% specificity for Ferning test, and 86.7% sensitivity & 81.3% specificity for Nitrazine test. The PPV and NPV of IGFBP-1 (Actim PROM test®) were 83.8% & 88.6% ...
Get Price2017-7-21 · fluid with a high concentration of IGFBP-1 mixes with vaginal secretions. In Actim PROM test, a specimen of vaginal secretion is taken with a sterile polyester swab and the specimen is extracted into Specimen Extraction Solution. The presence of IGFBP-1 in the solution is detected using a dipstick. The test is based on …
Get PriceType：hCG Pregnancy test/LH Ovulation test /FSH Menopause test /IGFBP-1(PROM) test fFN Fetal Fibronectin test Specimen:Urine/Serum/Secretion
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Get Price2018-9-11 · PROM from vaginal fluid4 (Figure 1). The majority of diagnostic PROM tests detect insulin-like growth factor binding protein-1 (IGFBP-1) present in vaginal ... * The Actim® PROM test has an IGFBP-1 measurement range of 400–8,000,000 µg/L. 400 µg/L corresponds to 25 µg/L in extracted sample.
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Get Price2004-7-1 · IGFBP-1 in the cervicovaginal fluid was measured by a rapid dipstick method (PROM test). AFI was measured by the four-quadrant method and an AFI of 80 mm was considered as oligohydroamnios. The sensitivity, specificity and accuracy of the nitrazine test, the PROM test and AFI were 97, 16 and 56%, 97, 97 and 97% and 94, 91 and 92%, …
Get Price2021-3-30 · PROM (IGFBP-1) Test Kits; Tumor Marks Tests. Fecal Occult Blood Test series ... together with Sale Manager and other sales, show main product,like HCG Pregnancy Test,LH Ovulation Test,Fecal Occult Blood Series Test, Bacterial Vaginosis Test Kit and so on,which attracted many customer’s attention. ... manufacturing, …
Get Price2004-6-28 · The sensitivity and specificity of diagnosing PROM by IGFBP-1 detection depend on the determined cutoff value of the IGFBP-1 level and the reported levels vary from about 75% to 100% (2, 5, 7-10). The PROM test is strongly positive for values of IGFBP-1 above 50 µg/L and can detect IGFBP-1 at a minimum of 25 µg/L.
Get PriceResults. Eighty subjects (40 in each group) were included between 25 1/7 to 41 1/7 weeks of gestation. AmniSure ® diagnostic test demonstrated a sensitivity and specificity of 95 % (82.4–99.4) and 94.8 % (79.3–98) respectively and a positive and negative predictive value of 95 % (84.7–100) and 94.8 % (87.9–100) respectively. Actim™Prom diagnostic test …
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Get Price2015-2-24 · Diagnostic tests (nitrazine test, fern test, Insulin-like Growth Factor Binding Protein-1 “IGFBP-1” and Placental Alpha Microglobulin-1 “PAMG-1”) should be used when the diagnosis is not certain following history, examination with sterile speculum and ultrasonography evaluation.
Get Price2017-10-31 · INTENDED USE PRO∙Mcomplete™ is a simple and rapid qualitative immunochro- matographic test for in vitro detection of IGFBP-1 (Insulin-like Growth Factor-Binding Protein-1) and AFP (Alpha-FetoProtein) from amniotic fluid in a vaginal swab sample. PRO∙Mcomplete™ is a point-of-care test intended to aid in the detection …
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Get Price2020-4-8 · Finally, IGFBP-1 test results have repeatedly been shown to be unaffected by the presence of blood [01,21,22]. Indeed, the monoclonal antibody used in the Actim PROM test does not recognize the highly phosphorylated IGFBP-1 which is the predominant isoform in maternal and fetal blood and decidua [4].
Get Price2017-11-27 · Biocare Rotavirus, rota/adeno, adenovirus, H pylori antigen, pregnancy test, HBsAg, FOB, transferrin, FOB/TF, Lactoferrin, PROM IGFBP-1 lateral flow tests are our main products, all these products use the antibody manufactured by our R&D team, the antibody batch size is over 5 grams.
Get PriceCite as: Abdelazim IA, Abu-Faza M. Fetal Fibronectin (Quick Check fFn Test) Versus Insulin-Like Growth Factor Binding Protein-1 (Actim PROM Test) for Detection of Premature Rupture of Fetal Membranes.
Get Price• The only ROM diagnostic found to correlate 99% with indigo carmine intra-amniotic injection, recognized by ACOG as the ROM testing gold standard (7) • Demonstrated by multiple studies to be a more accurate aid in detecting PROM than other ROM tests, including IGFBP-1 (8, 9, 23, 26)
Get Price2019-9-18 · AFP μg/ml7 IGFBP-1 μg/ml6 100,000 10,000 1,000 100 10 ROM Plus uses a unique monoclonal and polyclonal antibody approach while looking for two protiens, AFP (alpha-fetoprotein) and IGFBP-1 (insulin growth factor binding protein-1), to improve overall test sensitivity.
Get PriceResults. Eighty subjects (40 in each group) were included between 25 1/7 to 41 1/7 weeks of gestation. AmniSure ® diagnostic test demonstrated a sensitivity and specificity of 95 % (82.4–99.4) and 94.8 % (79.3–98) respectively and a positive and negative predictive value of 95 % (84.7–100) and 94.8 % (87.9–100) respectively. Actim™Prom diagnostic test …
Get Price2021-6-17 · 2021-6-17 · IGFBP-1 is not usually present in the vagina, but after rupture of fetal membranes, amniotic fluid with a high concentration of IGFBP-1 mixes with vaginal secretions. In StrongStep® PROM test, a specimen of vaginal secretion is taken with a sterile polyester swab and the specimen is extracted into Specimen Extraction Solution.
Get PricePROM (IGFBP-1) Test Kits. We are a professional Chinese manufacturer. We provide customers with quality products and one-stop service. Browse our website for further information on what you need. In this directory, you will learn about the contents of the IGFBP-1 PROM Test Kits ,test kit,lh test strip,pregnancy home test,pregnancy test with ...
Get PriceType：hCG Pregnancy test/LH Ovulation test /FSH Menopause test /IGFBP-1(PROM) test fFN Fetal Fibronectin test Specimen:Urine/Serum/Secretion
Get PriceDescription. Designed for professional use and in vitro diagnostic. Rapid chromatographic immunoassay test for the qualitative detection of IGFBP-1 (insulin-like growth factor binding protein 1), a major protein marker in amniotic fluid, in a vaginal swab.. RELIABLE: Sensitivity (true positive rate): 97.6%
Get Price2017-7-21 · 2017-7-21 · the IGFBP-1 bedside test can be used for the diagnosis of PROM in women with or without bleeding both at term and preterm. Kallioniemi et al, 2014 “ ” Unlike other diagnostic tests, gestational age will not affect the accuracy in detecting the presence of IGFBP-1 since the high amniotic fluid-serum ratio of IGFBP-1 is retained …
Get Price2018-9-11 · 2018-9-11 · Meix Biochemica Klovinpellontie 3, FI-02180 Espoo, Finland, [email protected] www.medixbiochemica.com Comparison of eight commercial PROM tests: ACTIM® PROM IS THE ONLY TEST NOT REPORTING PROM FALSE POSITIVES FOR MATERNAL SERA, AND NOT EXHIBITING HOOK EFFECT Laura Kanto 1…
Get Price2017-7-21 · 2017-7-21 · fluid with a high concentration of IGFBP-1 mixes with vaginal secretions. In Actim PROM test, a specimen of vaginal secretion is taken with a sterile polyester swab and the specimen is extracted into Specimen Extraction Solution. The presence of IGFBP-1 in the solution is detected using a dipstick. The test is based on …
Get Price2015-2-24 · 2015-2-24 · Diagnostic tests (nitrazine test, fern test, Insulin-like Growth Factor Binding Protein-1 “IGFBP-1” and Placental Alpha Microglobulin-1 “PAMG-1”) should be used when the diagnosis is not certain following history, examination with sterile speculum and ultrasonography evaluation.
Get PriceCite as: Abdelazim IA, Abu-Faza M. Fetal Fibronectin (Quick Check fFn Test) Versus Insulin-Like Growth Factor Binding Protein-1 (Actim PROM Test) for Detection of Premature Rupture of Fetal Membranes.
Get Price2017-7-21 · 2017-7-21 · binding protein-1 as a diagnostic tool for rupture of the membranes. J Obstet Gynecol Res (1998) 24: 411–417. 6. Palacio et al. BMC Pregnancy and Childbirth 2014, 14:183 7. Ragosch V et al. Insulin like growth factor binding protein 1 (IGFBP-1) und fetales Fibronectin in der Diagnostik eines vorzeitigen Blasensprunges. GebFra (1996) 56:1…
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Get PricePrezenta IGPBP – 1 in lichidele vaginale indica ruptura de membrana. Actim™PROM poate fi folosit chiar si in primele luni de sarcina. Concentratia de IGFBP – 1 in lichid amiotic este de 100-1000 ori mai mare
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Get PriceActim PROM test is a visually interpreted, qualitative immunochromatographic dipstick test for detection of amniotic fluid in vaginal secretions during pregnancy. Actim PROM detects IGFBP-1, which is a major protein in amniotic fluid and a marker of the amniotic fluid in a vaginal sample.
Get Price1998-12-1 · Objective:To evaluate the diagnostic value of insulin‐like growth factor binding protein‐1 (IGFBP‐1) as an indicator of ruptured fetal membranes. Methods:IGFBP‐ 1 concentrations were measured on 42 paired cervicovaginal samples before and after membrane rupture, using an immunoenzymatic assay. A PROM test (dipstick detecting IGFBP‐1 with a cutoff value of 25 μg/l (A)), a BTB test …
Get Price2018-7-4 · Actim Partus. 3.1 Actim Partus is a CE‑marked qualitative immunochromatographic point-of-care test designed to detect phosphorylated IGFBP‑1 (insulin-like growth factor binding protein‑1) in cervical secretions during pregnancy. Phosphorylated IGFBP‑1 is a protein made by the cells lining the uterus. When delivery is imminent, small amounts of phosphorylated IGFBP‑1 …
Get Price2010-11-1 · Purpose: To compare insulin-like growth factor binding protein-1 (IGFBP-1) (non-phosphorylated), placental alpha-microglobulin-1 (PAMG-1) and nitrazine test to diagnose premature rupture of membrane to allow gestation-specific management. Methods: We recruited 100 women with signs or symptoms of premature rupture of membranes (PROM…
Get PriceInsulin-like growth factor binding protein 1 (IGFBP-1 [Actim PROM]) is secreted by decidual and placental cells and has a very high concentration in amniotic fluid. This test is not affected by the presence of infected vaginal secretions, urine, semen or small amounts of blood. It, too, is a point-of-care test providing results in 5–10 minutes. 5
Get Price2010-8-13 · IGFBP-1 was performed in 94 women, the sensitivity was 87.5%, specificity was 94.4%, PPV was 92.1% and NPV was 91.1%. In 98 women in whom nitrazine test was performed, the sensitivity was 85%, specificity was 39.7%, PPV was 49.3% and NPV was 79.3%. Conclusion
Get Price2012-9-17 · The most commonly used conventional diagnostic for PROM is the sterile speculum examination (SSE). ... concluded in a comparative study of AmniSure and Actim PROM that the PAMG-1 test (AmniSure) seemed to be a more sensitive immunoassay test when compared with the IGFBP-1 test (Actim PROM). 9 Tagore and Kwek (2010), …
Get Price2012-2-22 · These markers include AFP, fetal fibronectin, IGFBP-1, prolactin, β-hCG, urea, lactate, placental alpha-microglobulin-1 and 2, and creatinine. 9. This is the fourth study to use vaginal fluid creatinine determination for the diagnosis of PROM. Li HY et al. 7 found that measurement of creatinine in vaginal fluid is cheaper and easier than hCG.
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Get PriceDescription. Designed for professional use and in vitro diagnostic. Rapid chromatographic immunoassay test for the qualitative detection of IGFBP-1 (insulin-like growth factor binding protein 1), a major protein marker in amniotic fluid, in a vaginal swab.. RELIABLE: Sensitivity (true positive rate): 97.6%
Get Price2020-7-8 · AMNIOQUICK ® DUO+ Rapid Premature Fibrosis (PROM) test kit uses immunochromatography to simultaneously and rapidly detect insulin-like growth factor binding protein 1 (IGFBP-1) and alpha-fetoprotein (AFP) in vaginal swab. IGFBP-1 is widely used as a diagnostic marker for premature rupture of amnion (PROM).
Get PricePRO•M complete ™ proposes an alternative tool to aid in the diagnosis of premature rupture of the fetal membranes by identification of IGFBP-1 ( I nsulin-like G rowth F actor- B inding P rotein-1) and AFP ( A lpha- F eto P rotein) from amniotic fluid in a vaginal swab sample. Only test that measures both IGFBP-1 and AFP separately.
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Get PriceProven Scientific Background The Actim PROM test is a rapid immunoassay that specifically detects Insulin-like Growth Factor Binding Protein-1 (IGFBP-1). IGFBP-1 is a subgroup of proteins of the insulin-like growth system, which has a function in the control mechanism of fetal and placental growth and development.
Get Price2016-7-17 · The Premature Rupture of Membranes or PROM is relatively frequent and ... IGFBP-1). TEST PRINCIPLE . A pair of monoclonal antibodies anti-IGFBP-1 is used for the IGFBP-1 detection. One is immobilized on the nitrocellulose membrane at the level of the B test line: it corresponds to the capture antibody. ... - As with all diagnostic tests, the ...
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Get Price2021-7-25 · (n= 125 and n=90), as well as high false positive 1,3 rates of 19-30%. Actim PROM rapid test detects insulin-like growth factor binding protein-1 (IGFBP-1) present in amniotic fluid as a marker of the presence of amniotic fluid in a cervicogenic sample. IGFBP-2
Get Price2021-5-27 · IGFBP-1:ta sisältävää lapsivettä pääsee vuotamaan vaginaan, jolloin myös vaginan IGFBP-1-pitoisuus kohoaa. Actim PROM havaitsee lapsiveden IGFBP-1:n vagina- näytteestä (Kuva 1). Actim PROMin menetelmä perustuu monoklonaalisiin vasta-aineisiin, jotka havaitsevat lapsiveden sisältämät IGFBP-1-proteiinin vähemmän fosfory -
Get Pricetest), have limitations in terms of cost, simplicity, and diagnostic accuracy, especially with passage of time since membrane rupture. However, the gold stand-ard for diagnosis of PROM, amnio-dye test, is inva-sive and carries risks of infection, abruption, and abortion.7 In recent years, researchers have focused on detect-
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Get Price2021-7-25 · The PROM Rapid Test is a rapid qualitative immunochromatographic test for the detection of IGFBP-1 in vaginal secretions. The test is intended for use by health care professionals as an aid in the diagnosis of premature rupture of amniotic membranes (prom) in pregnant women where prom is suspected. Interpretation of Results
Get PriceThe Alere Actim PROM test is an accurate aid in the diagnosis of suspected Premature Rupture of Membranes. It is a rapid immunoassay that specifically detects Insulin-like Growth Factor Binding Protein -1 (IGFBP-1). IGFBP-1 accumulates at high concentrations in amniotic fluid. When the membranes are ruptured, IGFBP-1 is detectable in a vaginal ...
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Get Price2004-7-1 · IGFBP-1 in the cervicovaginal fluid was measured by a rapid dipstick method (PROM test). AFI was measured by the four-quadrant method and an AFI of 80 mm was considered as oligohydroamnios. The sensitivity, specificity and accuracy of the nitrazine test, the PROM test and AFI were 97, 16 and 56%, 97, 97 and 97% and 94, 91 and 92%, …
Get PriceGrowth Factor-Binding Protein-1 (IGFBP-1) ou Placental Alpha 1-Microglobulin (PAMG-1). Mots-clés Diagnostic Rupture Tests biologiques Highlights » When typical endocervical fluid leakage is observed, the diagnosis of rupture of membranes can be confirmed with no additional biological test. » Biological tests are helpful
Get Price2021-7-3 · 1. AmniSure ROM (Rupture of [fetal] Membranes) Test Instructions for Use. QIAGEN, 2019. 2. ROM plus Rupture of Membranes Test Instructions for Use. P/N 050-0642 REV E, 2016. 3. Actim PROM Instructions for …
Get Price2020-10-16 · PROM Rapid Test Device 500150 Spécimen: Écouvillon Langue: Anglais Version: 01 Date d'entrée en vigueur: 2015-05 À usage professionnel de diagnostic in vitro uniquement. UTILISATION PRÉVUE Le test StrongStep® PROM est un test immunochromatographique qualitatif interprété visuellement pour la détection de l'IGFBP-1 …
Get Price2017-10-10 · con la prueba PAMG-1 (Amnisure) y 28,9 % con la IGFBP-1 (Actim-Prom); el único caso dispar resultó positivo a la amnionfusión con índigo de carmín. La concordancia entre ambas pruebas fue de 0,97. Conclusión: la IGFBP-1 demostró un desempeño similar a la PAMG-1 para el diagnóstico de ruptura de membranas.
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