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    2021-1-14 · 1000 times higher than in maternal serum. IGFBP-1 is not usually present in the vagina, but after rupture of fetal membranes, amniotic fluid with a high concentration of IGFBP-1 mixes with vaginal secretions. In the Alere Actim PROM test, a specimen of vaginal secretion is taken with a sterile polyester

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    2014-2-7 · The Actim PROM test is a visually interpreted, qualitative immunoassay rapid test for the detection of amniotic fluid in cervicovaginal secretions during pregnancy. The Actim PROM test detects IGFBP-1, a major protein in amniotic fluid and a marker of the presence of amniotic fluid in a vaginal sample. The test is intended for prescription use in

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  • Insulin-like Growth Factor-binding Protein 1 (IGFBP-1 ...

    2 天前 · Insulin-like growth factor-binding protein 1 is a member of the family of structurally homologous proteins that specifically binds and modulates the activities of IGF-1 and IGF-2. 1,2 IGFBP-1 is a 25 kilodalton protein that is produced predominantly by hepatocytes and decidualized ovarian endometrium. 3 Serum levels of IGFBP-1 exhibit considerable diurnal variation with levels highest early in ...

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  • International Journal of Women's Health and

    We aimed to investigate the diagnostic ability of the tests in PROM. Materials and Methods: Nitrazine test, fern test, amnio-dye test, biochemical tests (insulin-like growth factor binding protein-1 and placental alpha microglobulin-1) were evaluated in terms of effectiveness in diagnosis of PROM.

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  • Evaluation of the performance of the insulin-like

    2020-4-8 · Finally, IGFBP-1 test results have repeatedly been shown to be unaffected by the presence of blood [01,21,22]. Indeed, the monoclonal antibody used in the Actim PROM test does not recognize the highly phosphorylated IGFBP-1 which is the predominant isoform in …

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    Deep Blue Medical has already passed the CE and ISO13485 quality management system. Our main products are COVID-19 Rapid Antigen Test , COVID-19 Rapid Antibody Test, Infectious Disease Tests, HCG Pregnancy Test Strips, LH Ovulation Test Strips, Fecal Occult Blood Test series, IGFBP-1 PROM Test Kits and so on.

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  • Preterm Birth and PROM Testing Market | Global

    2021-3-23 · Our main products are HCG Pregnancy Test Strips, LH Ovulation Test Strips, Fecal Occult Blood Test series, IGFBP-1 PROM Test Kits, Bacterial Vaginosis Test series, PCT Test Kits and Medical Ultrasonic Couplant and so on, cover three categories of gynecological maternity, family planning and digestive medicine.

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  • certificate-Pregmate Ovulation Test,Diagnostic

    2018-7-4 · Actim Partus. 3.1 Actim Partus is a CE‑marked qualitative immunochromatographic point-of-care test designed to detect phosphorylated IGFBP‑1 (insulin-like growth factor binding protein‑1) in cervical secretions during pregnancy. Phosphorylated IGFBP‑1 is a protein made by the cells lining the uterus. When delivery is imminent, small amounts of phosphorylated IGFBP‑1 leak into the cervix.

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  • 3 The diagnostic tests | Biomarker tests to help

    Objective: To determine the accuracy of Actim PROM ®, Amnisure ®, and ROM Plus ® tests for detecting amniotic fluid proteins in the setting of blood contamination. Methods: IGFBP-1 and AFP are proteins present in high concentrations in amniotic fluid, and are detected by three commercially-available immunoassays used for diagnosing ruptured membranes: Actim PROM ®, Amnisure ®, and ROM ...

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  • Effect of blood contamination on amniotic fluid

    Proven Scientific Background The Actim PROM test is a rapid immunoassay that specifically detects Insulin-like Growth Factor Binding Protein-1 (IGFBP-1). IGFBP-1 is a subgroup of proteins of the insulin-like growth system, which has a function in the control mechanism of …

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  • Alere Actim PROM Brochure - Alere - PDF Catalogs ...

    Cite as: Abdelazim IA, Abu-Faza M. Fetal Fibronectin (Quick Check fFn Test) Versus Insulin-Like Growth Factor Binding Protein-1 (Actim PROM Test) for Detection of Premature Rupture of Fetal Membranes.

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  • Fetal Fibronectin (Quick Check fFn Test) Versus Insulin ...

    Cost-effective test for in vitro diagnostics. The 4-step test procedure detects placental alpha microglobulin-1 (PAMG-1) protein that is found in high concentrations in amniotic fluid and low concentrations in cervicovaginal fluid. 5. Saves time and the costs of additional ROM diagnostic methods. No confirmatory test required for a positive ROM ...

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  • In Vitro Technologies :: AmniSure

    The AmniSure ROM Test detects placental alpha microglobulin-1 (PAMG-1) in the vaginal discharge of pregnant patients presenting with signs, symptoms or complaints suggestive of PROM. Regardless of gestational age, high concentrations of PAMG-1 exist in amniotic fluid (2000–25,000 ng/ml), but low concentrations are found in the background vaginal

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  • Your Answer Can Impact a Life. Evaluate PROM

    Main Products: HCG Pregnancy Test Strips, LH Ovulation Test Strips,Fecal Occult Blood Test series,IGFBP-1 PROM Test Kits,Bacterial Vaginosis Test series,PCT Test Kits and Medical Ultrasonic Couplant and so on If there is chance we can operate, please ...

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    2021-7-27 · Impact Socket Set, Meterk 1/2' Drive Deep Impact Socket Set 20 PCS, 9-24 mm, 16 PCS Metric Sockets with 3/8' to 1/2' Socket Wrench Adapter and 3 PCS 1/2' Drive Impact Extension Bar. 88.99. 38.99. Free Shipping. SHOP NOW. Customer Service Send Feedback. Discounted prices and/or promo codes expire at 11:59PM PT on 04/23/2021 and valid in ...

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  • Biosynex Obstetrics Rapid Diagnostic Kit (Colloidal

    2020-7-8 · AMNIOQUICK ® DUO+ Rapid Premature Fibrosis (PROM) test kit uses immunochromatography to simultaneously and rapidly detect insulin-like growth factor binding protein 1 (IGFBP-1) and alpha-fetoprotein (AFP) in vaginal swab. IGFBP-1 is widely used as a diagnostic marker for premature rupture of amnion (PROM).

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  • ACTIM PROM - MD Doctors Direct

    2020-8-10 · IGFBP-1 is not usually present in the vagina, but af - ter rupture of fetal membranes amniotic fluid with a high concentration of IGFBP-1 mixes with vaginal se-cretions. In the Actim PROM test a specimen of vag - inal secretion is taken with a sterile polyester swab and the specimen is extracted into Specimen Extrac-tion Solution.

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  • Alere Actim Prom Test - Abbott Actim PROM Test ...

    The Alere Actim PROM test is an accurate aid in the diagnosis of suspected Premature Rupture of Membranes. It is a rapid immunoassay that specifically detects Insulin-like Growth Factor Binding Protein -1 (IGFBP-1). IGFBP-1 accumulates at high concentrations in amniotic fluid. When the membranes are ruptured, IGFBP-1 is detectable in a vaginal ...

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  • PPROM: what the evidence tells us – O&G Magazine

    Insulin-like growth factor binding protein 1 (IGFBP-1 [Actim PROM]) is secreted by decidual and placental cells and has a very high concentration in amniotic fluid. This test is not affected by the presence of infected vaginal secretions, urine, semen or small amounts of blood. It, too, is a point-of-care test providing results in 5–10 minutes. 5

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  • Evaluation of a rapid strip test for insulin-like growth ...

    1996-9-30 · After contractions, vaginal bleeding and cervical dilatation were included in a multiple logistic regression model, a positive PROM TEST result was shown to be a highly significant independent predictor of preterm delivery (P = 0.0001, odds ratio 44.3, 95% confidence interval 16.2-121.1). After the dipstick test, IGFBP-1 concentrations were ...

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    Our main products are HCG Pregnancy Test Strips, LH Ovulation Test Strips, Fecal Occult Blood Test series, IGFBP-1 PROM Test Kits, Bacterial Vaginosis Test series, PCT Test Kits and Medical Ultrasonic Couplant and so on, cover three categories of gynecological maternity, …

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  • Preterm Birth and PROM Testing Market Size Worth

    The global preterm birth and PROM testing market size is expected to reach USD 1.3 billion by 2025, according to a new report by Grand View Research, Inc., exhibiting a CAGR of 1.8% during the forecast period. Rising incidence of preterm births, increasing geographical reach by market players, high demand for effective diagnosis of preterm births, and advanced drug delivery devices are ...

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    2021-7-25 · The PROM Rapid Test is a rapid qualitative immunochromatographic test for the detection of IGFBP-1 in vaginal secretions. The test is intended for use by health care professionals as an aid in the diagnosis of premature rupture of amniotic membranes (prom) in pregnant women where prom is suspected. Interpretation of Results

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  • Diagnostic Kits - Advy

    Actim PROM test is a visually interpreted, qualitative immunochromatographic dipstick test for detection of amniotic fluid in vaginal secretions during pregnancy. Actim PROM detects IGFBP-1, which is a major protein in amniotic fluid and a marker of the amniotic fluid in a vaginal sample.

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    Our main products are HCG Pregnancy Test Strips, LH Ovulation Test Strips, Fecal Occult Blood Test series, IGFBP-1 PROM Test Kits, Bacterial Vaginosis Test series, PCT Test Kits and Medical Ultrasonic Couplant and so on, cover three categories of gynecological maternity, …

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  • Actim PROM Controls A30800ETUS-IFU LR - CooperSurgical

    2020-7-7 · 2. Actim PROM Low Positive Control (40 μg/L) 3. Actim PROM High Positive Control (250 μg/L) 4. Actim Reconstitution Solution 5. Instructions for use The Positive Controls consist of purified human insulin-like growth factor binding protein-1 (IGFBP-1) in a buffered protein solution with BSA and Thimerosal as preservative. The Negative Control ...

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  • ACTIM Prom Brochure - CooperSurgical

    2020-7-7 · Actim PROM’s high specificity and sensitivity help to promote diagnostic accuracy, minimizing false negative and false positive results. TABLE 1. Actim PROM has the highest sensitivity, specificity, and accuracy in PROM diagnosis8 versus standard of care PROM tests. Sensitivity % Specificity % Accuracy % Actim PROM test 97 97 97

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  • RESEARCH ARTICLE Open Access Meta-analysis of studies

    2017-8-27 · predefined search terms: PAMG-1 test, IGFBP-1 test, PAMG-1 PROM test, IGFBP-1 PROM test, placental alpha microglobulin-1 PROM test, insulin-like factor binding protein-1 PROM test, AmniSure® and Actim® PROM. All abstracts, full texts and citations were reviewed to select the papers in which: a) the rapid tests were

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  • Premature Rupture of Membranes - The Pregnancy Lab

    Also, ultrasound imaging of the amniotic fluid volume may also assist in diagnosis of PROM, but in individual cases such imaging may be difficult to interpret. Given the low but finite risk of complications of the dye test, the AFP and IGFBP-1 tests are often preferred as first-line tests for preterm premature rupture of membranes.

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  • Clinical Policy: Testing for Rupture of Fetal Membrane s

    2021-7-22 · (n= 125 and n=90), as well as high false positive rates of 19-30%.1,3-4 Actim PROM rapid test detects insulin-like growth factor binding protein-1 (IGFBP-1) present in amniotic fluid as a marker of the presence of amniotic fluid in a cervicogenic sample. IGFBP-2

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    2017-6-30 · strong diagnostic test for pre-term labour risk.15 Insulin-like growth factor binding protein-1 (IGFBP-1) functions in the control of foetal and placental growth and development.16,17 IGFBP-1 is produced by the decidual cells of the endometrium during pregnancy and it is found at high concentrations in amniotic fluid.17

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    Also, ultrasound imaging of the amniotic fluid volume may also assist in diagnosis of PROM, but in individual cases such imaging may be difficult to interpret. Given the low but finite risk of complications of the dye test, the AFP and IGFBP-1 tests are often preferred as first-line tests for preterm premature rupture of membranes.

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  • Alpha-fetoprotein - The Pregnancy Lab

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    2019-5-18 · e cost-effectiveness of the PAMG-1 test compared with the traditional diagnostic test of pooling, Nitrazine, and ferning in diagnosing preterm premature rupture of membranes in a resource-limited setting. The primary health outcome of interest is the number of hospital transfers averted by each strategy per 1,000 patients screened. Baseline probabilities and cost assumptions were derived from ...

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